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Hutchinson's sign; periungual pigmentation

Etiology: - pigmentation of the fingernail (brown nail) also involving the proximal nail fold is suggestive of acral lentiginous melanoma - melanoma until proven otherwise Clinical manifestations: 1) brown-black discoloration of the proximal & lateral nail folds - may appear to spread proximally from the proximal nail fold, not involving the nail [2] 2) brown-black pigmentation of the nail matrix, nail bed & nail plate obliterating the lunula 3) nail plate may show dystrophic changes

Related

Hutchinson's teeth; Hutchinson's incisor; Hutchinson-Boeck teeth Hutchinson's triad

General

sign/symptom

References

  1. Color Atlas & Synopsis of Clinical Dermatology, Common & Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY, 1997, pg 503
  2. Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025